CRISPR-based gene drives offer promising prospects for controlling disease-transmitting vectors and agricultural pests.A significant KERATIN COND challenge for successful suppression-type drive is the rapid evolution of resistance alleles.One approach to mitigate the development of resistance involves targeting functionally constrained regions usin
This review addresses the function of the protein-transporter glycoprotein-P (Pgp, ABCB1 protein) and the expression of its encoding gene MDR1/mdr1 throughout the gestational period KERATIN COND in humans and animals.We discuss the relationship between the transporter function and the hormone fluctuations during pregnancy.We cite studies on the ass
The aim of this study was to investigate the effect of nerve growth factor (NGF) administration on retinal ganglion cells (RGCs) in experimentally induced glaucoma (GL) and diabetic retinopathy (DR).GL was induced in adult rats by injection of hypertonic saline into the episcleral vein of the eye and VGAN5 + VANILLA diabetes (DT) was induced by adm